Brand name:
Zanaflex
Pronounced: ZAN-uh-flecks
Generic name:
Tizanidine
Why is Zanaflex prescribed?
Zanaflex relaxes the tense, rigid muscles caused by spasticity.
It is prescribed for people with multiple sclerosis, spinal cord
injuries, and other disorders that produce protracted muscles
spasms. The effect of the drug peaks 1 to 2 hours after each dose
and is gone within 3 to 6 hours, so it's best to schedule doses for
shortly before the daily activities when relief of spasticity is
most important.
Most important fact about Zanaflex
Zanaflex causes drowsiness in almost half the people who use it.
It also tends to reduce blood pressure in many people, frequently
leading to dizziness and light-headedness. The likelihood of
significant drowsiness increases when Zanaflex is combined with
other spasticity drugs, such as Lioresal, Klonopin, and Valium. When
taking Zanaflex, always be cautious about driving or operating
dangerous machinery.
How should you take Zanaflex?
Take Zanaflex exactly as directed. The danger of side effects
increases with the size of the dose.
--If you miss a dose...
Doses should be taken only as needed. Allow 6 to 8 hours between
doses. Take no more than 3 a day. Never double the dose.
--Storage instructions...
Store at room temperature.
Zanaflex side effects
Side effects cannot be anticipated. If any develop or change in
intensity, tell your doctor as soon as possible. Only your doctor
can determine if it is safe to continue using Zanaflex.
- Side effects may include:
Abnormal movements,
blurred vision,
constipation,
dizziness,
drowsiness,
dry mouth,
flu-like symptoms,
frequent urination,
low blood pressure,
nervousness,
runny nose,
slow heartbeat,
sore throat,
speech disorders,
urinary and other infections,
vomiting,
weakness or fatigue
Why should Zanaflex not be prescribed?
You'll need to avoid Zanaflex if it gives you an allergic
reaction.
Special warnings about Zanaflex
Researchers have little information on the long-term consequences
of using Zanaflex in single doses of more than 8 milligrams, or in
total amounts of more than 24 milligrams a day. If you require a
higher dosage, previously unrecognized side effects could possibly
appear.
Remember that Zanaflex can cause low blood pressure and should be
used with caution if you are taking blood pressure medication. Be
cautious, too, when first standing up. Dizziness and
light-headedness are especially likely at that time.
Zanaflex has been known to cause liver injury in a few patients.
If you have a liver condition, make sure the doctor knows about it.
Alert your doctor immediately if you develop warning signs of a
liver problem such as loss of appetite, nausea, vomiting, or yellow
skin or eyes.
You'll need a reduced dose of Zanaflex if you have a kidney
problem. Be sure to inform the doctor about your condition, and be
quick to report side effects such as dry mouth, drowsiness,
dizziness, and weakness. They could be signs that your dose is too
high.
Use Zanaflex with caution if spasticity helps you maintain your
posture and balance while walking, or helps to increase other
functions.
Although there are no reports of eye damage from Zanaflex, it has
occurred in animal tests. Be sure to report any vision problems to
your doctor.
Zanaflex has not been tested in children.
Possible food and drug interactions when taking Zanaflex
Oral contraceptives tend to boost the amount of Zanaflex in the
system. If you are using an oral contraceptive, you'll probably need
a smaller dose of Zanaflex.
Alcohol, or any drug that slows the nervous system (including
other drugs taken for spasticity), increases the likelihood of
drowsiness when taken with Zanaflex.
Special information if you are pregnant or breastfeeding
The effects of Zanaflex during pregnancy have not been adequately
studied. It should be used during pregnancy only if clearly needed.
It's likely that Zanaflex makes its way into breast milk,
although this has not been confirmed. Check with your doctor before
using Zanaflex while nursing.
Recommended dosage for Zanaflex
ADULTS
Overdosage
An overdose of Zanaflex can impair breathing and lead to coma. If
you suspect an overdose, seek emergency treatment immediately.
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